The Collaborative Research Centre (SFB) KIDGEM 1140 “ Kidney Disease – From Genes to Mechanisms” is funded by the Deutsche Forschungsgemeinschaft (DFG) and proposes to analyze genes associated with kidney disease and translate gene function into an understanding of molecular renal physiology. To achieve a systematic integrated approach to hereditary kidney disease, KIDGEM has assembled a consortium of physicians and scientists providing a broad spectrum of techniques, animal models as well as access to patient populations. The elucidation of pathologic molecular mechanisms aims to facilitate the diagnosis, treatment and prevention of hereditary kidney diseases. The SFB 1140 is organized into 15 scientific and 2 central projects and started at January 1st, 2015. The speaker of this SFB is Gerd Walz, Director of the Department of Internal Medicine IV of the University Medical Center in Freiburg.